Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA7 | P43166 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497198 | 0.84 | SMN1; SMN2 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16236650 | 0.81 | MAPT (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22380375 | 0.81 | BAZ2B (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4511766 | 0.81 | LMNA (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9826739 | 0.79 | KDM4E (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7189434 | 0.78 | LMNA (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9825664 | 0.76 | MAPT (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31540154 | 0.75 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31540157 | 0.75 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25240040 | 0.74 | LMNA (0.44) | MAPTALDH1A1GAALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735400-A | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-02-23 | — | — | CN | disclosed |