Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123020 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4ERAB9AHCRTR1TSHR | |
| SCHEMBL9497198 | 0.80 | SMN1; SMN2 (0.48) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL28199372 | 0.78 | CA12 (0.50) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL4511766 | 0.77 | LMNA (0.51) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL16236650 | 0.77 | MAPT (0.45) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL22380375 | 0.77 | BAZ2B (0.49) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL25240040 | 0.71 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL13593132 | 0.70 | LMNA (0.41) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2888240 | 0.69 | TSHR (0.55) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL11249719 | 0.69 | CA12 (0.56) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1360176-A1 | PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002064562-A1 | PYRROLECARBOXAMIDES FOR THE USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-08-22 | — | — | WO | disclosed |