Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262898 | 0.80 | KDM4E (0.44) | BCAT2TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL27602498 | 0.79 | GABBR2 (0.44) | TSHRKDM4ECYP2C19GABBR2GABBR1 | |
| SCHEMBL2320833 | 0.78 | CTSA (0.47) | GABBR2GABBR1CTSA | |
| SCHEMBL5597477 | 0.78 | AKR1B1 (0.44) | TSHRKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL5918770 | 0.78 | AKR1B1 (0.44) | TSHRKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL2320843 | 0.78 | CTSA (0.47) | GABBR2GABBR1CTSA | |
| SCHEMBL5720952 | 0.78 | CTSA (0.47) | GABBR2GABBR1CTSA | |
| SCHEMBL31757740 | 0.78 | AKR1B1 (0.44) | TSHRKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL25253132 | 0.76 | CTSA (0.47) | GABBR2GABBR1KMT2ACTSA | |
| SCHEMBL5720972 | 0.76 | GABBR2 (0.42) | TSHRHPGDCYP2C19GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709334-A | New amino acid derivativges, its preparation method and include their Pharmaceutical composition | 法国施维雅药厂 | 2018-02-16 | — | — | CN | disclosed |