Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839451 | 0.85 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL474162 | 0.83 | KDM4E (0.45) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL20549769 | 0.83 | CYP3A4 (0.48) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11503111 | 0.81 | KDM4E (0.44) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8526511 | 0.81 | TSHR (0.55) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL1380696 | 0.81 | TSHR (0.55) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL21436026 | 0.81 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL8366891 | 0.80 | LMNA (0.52) | KDM4EMAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL4976973 | 0.80 | RPS6KB1 (0.44) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL28199566 | 0.80 | BCAT2 (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655396-B1 | Methods for detecting receptor modulator activity | ALLERGAN, INC. (US) | 2010-02-02 | — | — | US | disclosed |