Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | WEE1 | P30291 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743220 | 0.86 | KIF11 (0.47) | CDK4CCND1KIF11MEN1NPC1 | |
| SCHEMBL19773080 | 0.82 | CDK4 (0.52) | CDK4CCND1CHEK1WEE1KIF11 | |
| SCHEMBL28057941 | 0.80 | KIF11 (0.43) | SIRT2KIF11MEN1NPC1POLB | |
| SCHEMBL30687932 | 0.80 | KIF11 (0.43) | SIRT2KIF11MEN1NPC1POLB | |
| SCHEMBL19494764 | 0.80 | CDK4 (0.56) | CDK4CCND1CHEK1WEE1MEN1 | |
| SCHEMBL28774313 | 0.79 | KIF11 (0.55) | KIF11MEN1NPC1POLBKMT2A | |
| SCHEMBL29888691 | 0.78 | CDK4 (0.55) | CDK4CCND1CHEK1WEE1NPC1 | |
| SCHEMBL25556376 | 0.77 | CDK4 (0.56) | CDK4CCND1CHEK1WEE1KIF11 | |
| SCHEMBL17231623 | 0.77 | IMPDH2 (0.45) | CDK4CCND1KIF11HPGDIMPDH2 | |
| SCHEMBL25618009 | 0.77 | CDK4 (0.49) | CDK4CCND1CHEK1WEE1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461613-B | Carbazole derivates grafted monomers, preparation method and its application in polyarylether polymer | 吉林大学 | 2018-02-09 | — | — | CN | claimed |