Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708736 | 0.81 | MAPT (0.51) | LMNAMAPTHTTSMN1; SMN2POLB | |
| SCHEMBL9384445 | 0.80 | PTGDR2 (0.53) | LMNAMAPTHTTSMN1; SMN2POLB | |
| SCHEMBL13370039 | 0.79 | ABCB1 (0.49) | MAPTHTTGAAPTGDR2MAPK1 | |
| SCHEMBL11736604 | 0.79 | PTGDR2 (0.53) | LMNAMAPTHTTSMN1; SMN2POLB | |
| SCHEMBL9157553 | 0.79 | MEN1 (0.62) | LMNAMAPTHTTSMN1; SMN2POLB | |
| Acrylic Acid SCHEMBL28199721 | 0.78 | MAPT (0.53) | LMNAMAPTHTTSMN1; SMN2POLB | |
| SCHEMBL29805146 | 0.78 | ELANE (0.58) | MAPTALDH1A1GAAPTGDR2MAPK1 | |
| SCHEMBL474832 | 0.78 | ELANE (0.58) | MAPTALDH1A1GAAPTGDR2MAPK1 | |
| SCHEMBL11640349 | 0.78 | PTGDR2 (0.53) | LMNAMAPTHTTSMN1; SMN2POLB | |
| SCHEMBL4655499 | 0.77 | TTR (0.49) | LMNAMAPTHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540646-A | Vilazodone intermediate synthetic method | 连云港恒运药业有限公司 | 2018-01-05 | — | — | CN | disclosed |