SCHEMBL4655499

SCHEMBL4655499

C=CC(=O)Oc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.49
ALDH1A1 P00352 6/20 0.48
MAPT P10636 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
HSPB1 P04792 3/20 0.48
GPR35 Q9HC97 2/20 0.47
HPGD P15428 2/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
LMNA P02545 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
POLB P06746 2/20 0.45
CYP1A2 P05177 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7126316 0.85 GPR35 (0.47) TTRALDH1A1MEN1KMT2AGPR35
SCHEMBL13048608 0.84 ALDH1A1 (0.52) ALDH1A1MAPTHPGDTSHRMAPK1
SCHEMBL427368 0.82 ALDH1A1 (0.55) TTRALDH1A1MAPTMEN1KMT2A
SCHEMBL29821424 0.82 ALDH1A1 (0.55) TTRALDH1A1MAPTMEN1KMT2A
SCHEMBL1220299 0.82 ALDH1A1 (0.55) TTRALDH1A1MAPTMEN1KMT2A
SCHEMBL29379815 0.82 ALDH1A1 (0.55) TTRALDH1A1MAPTMEN1KMT2A
SCHEMBL27361987 0.82 ERN1 (0.47) TTRALDH1A1MAPTMEN1KMT2A
SCHEMBL13048634 0.81 ALDH1A1 (0.46) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL2402141 0.81 TTR (0.55) TTRALDH1A1MAPTMEN1KMT2A
SCHEMBL2402136 0.81 TTR (0.55) TTRALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939219-A Copolymer of phenolic ester of (meth)acrylic acid KANSAI PAINT COMPANY, LIMITED (JP) 1990-07-03 US claimed
EP-0327021-A2 Coating compositions for preventing adhesion of aquatic organisms KANSAI PAINT CO. LTD. (JP) 1989-08-09 EP claimed
EP-4747690-A1 RELIEF FORMING PLATE PRECURSORS ECO3 BV (BE) 2026-05-27 EP disclosed
WO-2025056496-A1 A FLATBED LAMINATOR ECO3 BV (BE) 2025-03-20 WO disclosed
WO-2025017002-A1 RELIEF FORMING PLATE PRECURSORS ECO3 BV (BE) 2025-01-23 WO disclosed
WO-2025017000-A1 RELIEF FORMING PLATE PRECURSORS ECO3 BV (BE) 2025-01-23 WO disclosed
EP-4495691-A1 RELIEF FORMING PLATE PRECURSORS ECO3 BV (BE) 2025-01-22 EP disclosed
EP-1208238-B1 Methods of immobilizing ligands on solid supports MATRIX TECHNOLOGIES CORP (US) 2008-11-12 EP disclosed
US-20080194673-A1 Environment-Friendly Pollution-Proof Agent SOONCHUNHYANG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2008-08-14 US disclosed
US-20080071005-A1 Environment-Friendly Pollution-Proof Agent SOONCHUNHYANG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2008-03-20 US disclosed
EP-1771521-A4 ENVIRONMENT -FRIENDLY POLLUTION-PROOF AGENT EXTRACTED FROM SARGASSUM UNIV SOONCHUNHYANG IND ACAD COOP FOUND (KR) 2008-02-20 EP disclosed
US-20020115019-A1 Photosensitive flexographic printing element having at least two IR-ablative layers BASF DRUCKSYSTEME GMBHT (DE) 2002-08-22 US disclosed
EP-1069475-A1 Flexographic printing element comprising an IR-ablatable layer with high sensitivity BASF Drucksysteme GmbH (DE) 2001-01-17 EP disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0674325-A2 Electrically insulating polymer composition and wire or cable using the same Nippon Petrochemicals Co., Ltd. (JP) 1995-09-27 EP disclosed
US-4939219-A Copolymer of phenolic ester of (meth)acrylic acid KANSAI PAINT COMPANY, LIMITED (JP) 1990-07-03 US disclosed
EP-0327021-A2 Coating compositions for preventing adhesion of aquatic organisms KANSAI PAINT CO. LTD. (JP) 1989-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194673-A1 Environment-Friendly Pollution-Proof Agent TST, TBCD, TBCA TTR 519/4885ALDH1A1 2286/4885MAPT 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.