Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 4/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624718 | 0.92 | LMNA (0.60) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| Acrylic Acid SCHEMBL27645912 | 0.81 | POLB (0.68) | MAPTLMNAPOLBHTTFNTA | |
| SCHEMBL27497022 | 0.80 | GAA (0.60) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL27918601 | 0.79 | FNTA (0.47) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL27129636 | 0.79 | L3MBTL1 (0.67) | MAPTLMNAHTTSMN1; SMN2ALKBH5 | |
| SCHEMBL27402036 | 0.79 | ALDH1A1 (0.54) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL9384717 | 0.78 | KCNMA1 (0.62) | MAPTSMN1; SMN2ALKBH5FTOALDH1A1 | |
| SCHEMBL333161 | 0.78 | MAPT (0.62) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL6815300 | 0.78 | MAPT (0.62) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL27003686 | 0.78 | L3MBTL1 (0.58) | MAPTSMN1; SMN2ALKBH5FTOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540646-A | Vilazodone intermediate synthetic method | 连云港恒运药业有限公司 | 2018-01-05 | — | — | CN | disclosed |