SCHEMBL28199752

SCHEMBL28199752

C=C(N=[N+]=[N-])c1ccccc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.43
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CHRNB2 P17787 4/20 0.39
CHRNA4 P43681 4/20 0.39
CHRNB4 P30926 3/20 0.39
CHRNA3 P32297 3/20 0.39
HNF4A P41235 1/20 0.37
TSHR P16473 1/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
HTT P42858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347361 0.87 SLC6A4 (0.45) BCAT2MEN1KMT2AHTT
SCHEMBL28350699 0.87 SLC6A4 (0.45) BCAT2MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL28199201 0.87 HNF4A (0.40) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL28280696 0.85 PDCD1 (0.42) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL28350925 0.83 ABL1 (0.44) MEN1KMT2ASMN1; SMN2GAALMNA
SCHEMBL28366720 0.83 RORB (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1CASP3
SCHEMBL28363445 0.83 GAA (0.43) ALDH1A1HSD17B10GAABACE1
SCHEMBL28347326 0.82 PTGDR2 (0.35) MEN1KMT2ASMN1; SMN2TSHRALDH1A1
SCHEMBL28363161 0.82 BRD9 (0.32)
SCHEMBL28869522 0.82 HNF4A (0.33) BCAT2MEN1KMT2ASMN1; SMN2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110714208-B Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-12-29 CN claimed
CN-110714208-A Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-01-21 CN claimed
CN-109232420-B Method for synthesizing 6-sulfone methyl phenanthridine derivatives through visible light catalysis 上饶师范学院 2021-12-24 CN disclosed
CN-110714208-B Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-12-29 CN disclosed
CN-110684989-B Method for electrochemically synthesizing 6-azido methyl phenanthridine compound 常州工学院 2020-08-04 CN disclosed
CN-110862348-A Synthetic method of 6-cyanophenanthridine compound 浙江工业大学 2020-03-06 CN disclosed
CN-110714208-A Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-01-21 CN disclosed
CN-110684989-A Method for electrochemically synthesizing 6-azido methyl phenanthridine compound 常州工学院 2020-01-14 CN disclosed
CN-109422683-A A method of synthesis 6- aldehyde radical phenanthridines class compound and its derivative 浙江工业大学 2019-03-05 CN disclosed
CN-109422688-A A method of replacing phenanthridines class compound using xanthate synthesis 6- 浙江工业大学 2019-03-05 CN disclosed
CN-109422689-A A kind of 6- replaces the synthetic method of phenanthridines class compound 浙江工业大学 2019-03-05 CN disclosed
CN-109422687-A A method of synthesis 6- cyano phenanthridines class compound 浙江工业大学 2019-03-05 CN disclosed
CN-109422684-A A method of synthesis 6- methyl phenanthridines class compound 浙江工业大学 2019-03-05 CN disclosed
CN-109422665-A A kind of synthetic method of fluorine-containing imine compound and its derivative 浙江工业大学 2019-03-05 CN disclosed
CN-107641100-A A kind of method for synthesizing 6 cyano group phenanthridines class compounds 浙江工业大学 2018-01-30 CN disclosed