Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034179 | 0.75 | CHRM2 (0.37) | KDM4EDRD2L3MBTL1MEN1NPC1 | |
| SCHEMBL18948371 | 0.73 | CHRM2 (0.35) | KDM4EL3MBTL1MEN1NPC1KMT2A | |
| SCHEMBL11914063 | 0.72 | CHRM2 (0.34) | KDM4EL3MBTL1NPC1ALDH1A1FEN1 | |
| SCHEMBL15359058 | 0.69 | AXL (0.43) | L3MBTL1MEN1KMT2A | |
| SCHEMBL2971826 | 0.69 | KDM4E (0.50) | KDM4EHCRTR1HCRTR2L3MBTL1MEN1 | |
| SCHEMBL19038296 | 0.69 | AXL (0.57) | — | |
| SCHEMBL15334300 | 0.69 | AXL (0.57) | — | |
| SCHEMBL15847313 | 0.68 | ALDH1A1 (0.39) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL31306191 | 0.68 | KEAP1 (0.61) | KEAP1KDM4EL3MBTL1MEN1NPC1 | |
| SCHEMBL17239438 | 0.67 | NPC1 (0.44) | KDM4EHCRTR1HCRTR2DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104185627-B | Pyridone Derivatives | 第三共株式会社 | 2018-01-12 | — | — | CN | disclosed |