Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821480 | 0.91 | HSP90AB1 (0.44) | ALOX5KDM1AHSP90AB1TUBB4ATUBB | |
| SCHEMBL2820224 | 0.91 | ALOX5 (0.46) | ALOX5KDM1AHSP90AB1CYP19A1POLB | |
| SCHEMBL2821326 | 0.90 | ALOX5 (0.44) | ALOX5KDM1AHSP90AB1TUBB4ATUBB | |
| SCHEMBL2820612 | 0.89 | ALOX5 (0.42) | ALOX5KDM1AHSP90AB1TUBB4ATUBB | |
| SCHEMBL2819648 | 0.89 | HDAC1 (0.44) | ALOX5KDM1AHSP90AB1TUBB4ATUBB | |
| SCHEMBL2821368 | 0.89 | KDM1A (0.49) | ALOX5KDM1AHSP90AB1CYP19A1HDAC1 | |
| SCHEMBL2823580 | 0.88 | POLB (0.47) | ALOX5KDM1AHSP90AB1TUBB4ATUBB | |
| SCHEMBL2821425 | 0.87 | HDAC1 (0.45) | ALOX5KDM1AHSP90AB1TUBB4ATUBB | |
| SCHEMBL2822489 | 0.87 | HSP90AB1 (0.49) | ALOX5HSP90AB1CYP19A1POLBL3MBTL1 | |
| SCHEMBL2819542 | 0.85 | KDM1A (0.40) | ALOX5KDM1AHSP90AB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | ALOX5 570/4885KDM1A 4155/4885HSP90AB1 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.