Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821368 | 0.93 | KDM1A (0.49) | HSP90AB1ALOX5CYP19A1MEN1NPC1 | |
| SCHEMBL2821480 | 0.92 | HSP90AB1 (0.44) | HSP90AB1ALOX5CYP19A1MGAMPOLB | |
| SCHEMBL2823580 | 0.92 | POLB (0.47) | HSP90AB1ALOX5CYP19A1POLBL3MBTL1 | |
| SCHEMBL2821425 | 0.91 | HDAC1 (0.45) | HSP90AB1ALOX5CYP19A1MGAMLMNA | |
| SCHEMBL2821446 | 0.90 | HSP90AB1 (0.53) | HSP90AB1ALOX5CYP19A1MGAMPOLB | |
| SCHEMBL2819648 | 0.89 | HDAC1 (0.44) | HSP90AB1ALOX5MGAMTHRB | |
| SCHEMBL2820002 | 0.87 | ALOX5 (0.41) | HSP90AB1ALOX5CYP19A1MGAMPOLB | |
| SCHEMBL2819542 | 0.85 | KDM1A (0.40) | HSP90AB1ALOX5CYP19A1MGAMMEN1 | |
| SCHEMBL2826176 | 0.84 | ALOX5 (0.53) | HSP90AB1ALOX5CYP19A1MGAMPOLB | |
| SCHEMBL2821944 | 0.84 | LMNA (0.42) | L3MBTL1ALDH1A1LMNATHRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | HSP90AB1 937/4885ALOX5 570/4885CYP19A1 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.