Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809427 | 0.98 | LMNA (0.45) | LMNAAOC3POLBCHRM2CHRM1 | |
| SCHEMBL19809391 | 0.93 | LMNA (0.41) | LMNAAOC3POLBCHRM2CHRM1 | |
| SCHEMBL19809241 | 0.89 | LMNA (0.41) | LMNAAOC3POLBCHRM2CHRM1 | |
| SCHEMBL22661009 | 0.86 | LMNA (0.48) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28449691 | 0.82 | LMNA (0.36) | LMNAAOC3POLBCHRM2CHRM1 | |
| SCHEMBL19809323 | 0.82 | LMNA (0.48) | LMNAAOC3POLBTSHRHPGD | |
| SCHEMBL706074 | 0.81 | TAAR1 (0.38) | LMNACHRM2CHRM1CHRM3TSHR | |
| SCHEMBL19809149 | 0.78 | NPC1 (0.45) | LMNANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL702246 | 0.78 | LMNA (0.39) | LMNACHRM2CHRM1CHRM3TSHR | |
| SCHEMBL63381 | 0.78 | DPP4 (0.37) | LMNAAOC3CYP1A2CYP2D6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709464-A | Containing silicone resin composition | 东京应化工业株式会社 | 2018-02-16 | — | — | CN | disclosed |