SCHEMBL28200215

SCHEMBL28200215

NNC(=O)C(=O)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.41
GAA P10253 4/20 0.40
ALPL P05186 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
ALDH1A1 P00352 6/20 0.35
TSHR P16473 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 5/20 0.33
NCEH1 Q6PIU2 1/20 0.33
MAPK1 P28482 2/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 5/20 0.32
KDM4E B2RXH2 4/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
GFER P55789 1/20 0.31
PTK2B Q14289 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2929232 0.83 FABP3 (0.49) FABP3GAAMRGPRX4TSHRNPC1
SCHEMBL28856223 0.81 GAA (0.41) GAAALPLALDH1A1NPC1RAB9A
SCHEMBL5460219 0.78 FABP3 (0.49) FABP3MRGPRX4ALDH1A1TSHRNPC1
SCHEMBL28050334 0.77 HDAC6 (0.48) GAAALDH1A1RAB9ALMNAMAPT
SCHEMBL5790540 0.76 FABP3 (0.46) FABP3ALPLMRGPRX4TSHRNPC1
SCHEMBL30552290 0.75 FABP3 (0.49) FABP3MRGPRX4TSHRNPC1RAB9A
SCHEMBL121772 0.75 FABP3 (0.49) FABP3MRGPRX4TSHRNPC1RAB9A
SCHEMBL28856236 0.75 GAA (0.42) FABP3GAAALDH1A1TSHRNPC1
SCHEMBL9662600 0.75 FABP3 (0.43) FABP3MRGPRX4ALDH1A1TSHRNPC1
SCHEMBL1153425 0.75 FABP3 (0.43) FABP3MRGPRX4ALDH1A1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed