SCHEMBL28050334

SCHEMBL28050334

NNC(=O)C(=O)Oc1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
PTK2B Q14289 2/20 0.43
BCHE P06276 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 3/20 0.42
GAA P10253 2/20 0.41
MAPT P10636 3/20 0.40
CXCL8 P10145 1/20 0.39
RAB9A P51151 1/20 0.39
CTSD P07339 1/20 0.39
XIAP P98170 1/20 0.38
GFER P55789 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2947498 0.82 PTK2B (0.51) MEN1KMT2APKMPTK2BBCHE
SCHEMBL28200215 0.77 FABP3 (0.41) HDAC6PTK2BSMN1; SMN2LMNAGAA
SCHEMBL28856236 0.76 GAA (0.42) KMT2ASMN1; SMN2LMNAGAAMAPT
SCHEMBL5790498 0.76 MAPT (0.46) MEN1KMT2APKMPTK2BBCHE
SCHEMBL1827523 0.75 PTK2B (0.49) HDAC6MEN1KMT2APKMPTK2B
SCHEMBL31243755 0.75 PTK2B (0.49) HDAC6MEN1KMT2APKMPTK2B
SCHEMBL29450644 0.74 PTK2B (0.51) MEN1KMT2APKMPTK2BBCHE
SCHEMBL56863 0.74 PTK2B (0.51) MEN1KMT2APKMPTK2BBCHE
SCHEMBL9661038 0.74 BCHE (0.47) MEN1KMT2APKMPTK2BBCHE
SCHEMBL964110 0.74 ELANE (0.49) MEN1KMT2APKMPTK2BBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294482-A Preparation method for 2-chlorophenylhydrazine oxalate TIANJIN CHEM REAGENT RES INST 2016-02-03 CN claimed
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
CN-105294482-A Preparation method for 2-chlorophenylhydrazine oxalate TIANJIN CHEM REAGENT RES INST 2016-02-03 CN disclosed