SCHEMBL2929232

SCHEMBL2929232

O=C(Oc1ccc(Cl)c(Cl)c1Cl)C(=O)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.49
MRGPRX4 Q96LA9 1/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 1/20 0.41
TSHR P16473 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 4/20 0.35
NCEH1 Q6PIU2 2/20 0.35
TDP1 Q9NUW8 4/20 0.34
KDM4E B2RXH2 2/20 0.34
ALOX12 P18054 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5460219 0.90 FABP3 (0.49) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL121772 0.86 FABP3 (0.49) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL30552290 0.86 FABP3 (0.49) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL9662600 0.86 FABP3 (0.43) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL1153425 0.86 FABP3 (0.43) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL31105888 0.84 FABP3 (0.51) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL2849811 0.84 FABP3 (0.47) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL121773 0.84 FABP3 (0.51) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL28200215 0.83 FABP3 (0.41) FABP3MRGPRX4CYP3A4MAPK1TSHR
SCHEMBL8860109 0.83 KDM4E (0.50) FABP3MRGPRX4CYP3A4MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0432017-B1 Derivatives of tetrahydro-2,3,6,7,1H,5H,11H-(1)benzopyrano(6,7,8,ij)quinolizinone-11 usable as markers for organic compounds for the purpose of detecting said compounds by chemiluminescence or fluorescence EUROBIO LAB (FR) 1995-08-16 EP claimed
EP-0419542-B1 NEW DERIVATIVES OF TETRAHYDRO-2,3,6,7,1H,5H,11H-(1)BENZOPYRANO(6,7,8,IJ)QUINOLIZONONE-11 USABLE AS MARKERS FOR ORGANIC COMPOUNDS FOR THE PURPOSE OF DETECTING SAID COMPOUNDS BY CHEMILUMINESCENCE OR FLUORESCENCE LABORATOIRES EUROBIO (FR) 1993-09-29 EP claimed
US-20250064339-A1 SENSOR DEVICES AND SYSTEMS FOR MONITORING MARKERS IN BREATH BIOLUM SCIENCES LLC (US) 2025-02-27 US disclosed
US-11903695-B2 Sensor devices and systems for monitoring markers in breath BIOLUM SCIENCES LLC (US) 2024-02-20 US disclosed
US-20210041467-A1 METHODS FOR ASSESSING THE NEED FOR AND THE EFFECTIVENESS OF THERAPY WITH ANTIOXIDANTS THE PROIMMUNE COMPANY, LLC 2021-02-11 US disclosed
US-20200141956-A1 METHODS OF ASSESSING THE NEED FOR AND THE EFFECTIVENESS OF THERAPY WITH ANTIOXIDANTS THE PROIMMUNE COMPANY, LLC 2020-05-07 US disclosed
US-20160341748-A1 Methods of assessing the need for and the effectiveness of therapy with antioxidants CRUM ALBERT B (US) 2016-11-24 US disclosed
US-9229014-B2 Methods of assessing the need for and the effectiveness of therapy with antioxidants THE PROIMMUNE COMPANY, LLC 2016-01-05 US disclosed
EP-1934598-B1 DIAGNOSIS OF OBLIGATE INTRACELLULAR PATHOGENS PETYAEV IVAN MIKHAILOVICH (GB) 2010-09-22 EP disclosed
EP-1456670-B1 METHODS RELATING TO TREATMENT OF ATHEROSCLEROSIS CAMBRIDGE THERANOSTICS LTD (GB) 2009-07-15 EP disclosed
EP-1454140-B1 DIAGNOSIS AND TREATMENT OF ATHEROSCLEROSIS CAMBRIDGE THERANOSTICS LTD (GB) 2009-07-08 EP disclosed
US-4621059-A Apparatus for measuring velocity of enzyme reaction KABUSHIKI KAISHA TOSHIBA (JP) 1986-11-04 US disclosed
EP-0173375-A1 Novel assay product and process POLAROID CORPORATION (US) 1986-03-05 EP disclosed
EP-0156204-A2 Apparatus for measuring velocity of enzyme reaction KABUSHIKI KAISHA TOSHIBA (JP) 1985-10-02 EP disclosed
EP-0140521-A2 Specific binding assay Bayer Corporation (US) 1985-05-08 EP disclosed
EP-0032131-B1 5-HALO-PYRIMIDIN-2-ONES, THE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM NYEGAARD & CO. A/S (NO) 1983-09-21 EP disclosed
US-4396579-A IMMUNOASSAY MILES LABORATORIES, INC. (US) 1983-08-02 US disclosed
EP-0071859-A2 Luminescence detection device MILES LABORATORIES, INC. (US) 1983-02-16 EP disclosed
US-4365018-A SELF-EXPOSING, CHEMILUMINESCENCE THE MEAD CORPORATION (US) 1982-12-21 US disclosed
US-4313843-A CHEMILUMINESCENT HAVING GOOD STORAGE STABILITY AMERICAN CYANAMID COMPANY (US) 1982-02-02 US disclosed