Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110103 | 0.83 | DPP4 (0.38) | THRBKDM4EALDH1A1HSD17B10EGFR | |
| SCHEMBL11232285 | 0.80 | AHR (0.47) | CYP3A4 | |
| SCHEMBL11171012 | 0.79 | CYP3A4 (0.36) | THRBHSD17B10EGFRKMT2ACYP3A4 | |
| SCHEMBL30596859 | 0.79 | FABP3 (0.43) | THRBEGFRTHRAGSRKMT2A | |
| SCHEMBL1153847 | 0.79 | FABP3 (0.43) | THRBEGFRTHRAGSRKMT2A | |
| SCHEMBL29110139 | 0.78 | THRB (0.44) | THRBKDM4EALDH1A1HSD17B10EGFR | |
| SCHEMBL29137037 | 0.78 | THRB (0.37) | THRBKDM4EALDH1A1HSD17B10EGFR | |
| SCHEMBL460577 | 0.77 | THRB (0.36) | THRBALDH1A1HSD17B10THRATYMS | |
| SCHEMBL29656980 | 0.77 | THRB (0.36) | THRBALDH1A1HSD17B10THRACYP3A4 | |
| SCHEMBL6658293 | 0.77 | KMT2A (0.40) | THRBALDH1A1THRAGSRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709291-A | Inhibitors and uses thereof | 医疗研究局 | 2018-02-16 | — | — | CN | disclosed |