Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070513 | 0.87 | THRB (0.41) | KMT2AESR1ESR2ALDH1A1THRB | |
| SCHEMBL29657033 | 0.83 | THRB (0.42) | KMT2AESR1ESR2ALDH1A1GSR | |
| SCHEMBL20534013 | 0.81 | KMT2A (0.39) | KMT2ATSHRALDH1A1GSRTHRB | |
| SCHEMBL28624346 | 0.81 | KMT2A (0.39) | KMT2AALDH1A1GSRTHRBHPGD | |
| SCHEMBL28910060 | 0.81 | HPGD (0.40) | KMT2AALDH1A1GSRTHRBHPGD | |
| SCHEMBL10499684 | 0.81 | KDM4E (0.39) | KMT2AALDH1A1GSRTHRBHPGD | |
| SCHEMBL29110103 | 0.79 | DPP4 (0.38) | KMT2AALDH1A1GSRTHRBTYMS | |
| SCHEMBL4070955 | 0.78 | KMT2A (0.36) | KMT2ATSHRALDH1A1GSRTHRB | |
| SCHEMBL27730838 | 0.78 | BCL2A1 (0.38) | KMT2ATSHRALDH1A1GSRTHRB | |
| SCHEMBL6653138 | 0.77 | TP53 (0.47) | KMT2ATSHRESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431280-A1 | ARYL SULFAMATE DERIVATIVES | Kyowa Hakko Kogyo Co., Ltd (JP) | 2004-06-23 | — | — | EP | disclosed |