SCHEMBL28200533

SCHEMBL28200533

O=C(O)C1(C(=O)O)CCCCN1O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
AKR1C1 Q04828 1/20 0.31
HSD11B1 P28845 3/20 0.31
FFAR3 O14843 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3784396 0.79 FFAR3 (0.32) FFAR3
SCHEMBL1984087 0.79 FFAR3 (0.32) FFAR3
SCHEMBL940715 0.76 CYP2C19 (0.31) CYP2C19MEN1KMT2A
SCHEMBL3578695 0.76 CYP2C19 (0.31) CYP2C19MEN1KMT2A
SCHEMBL1991503 0.76
SCHEMBL2544922 0.74 SLC18A3 (0.32)
SCHEMBL8342630 0.74
SCHEMBL28743535 0.73 CYP2C19 (0.32) CYP2C19MEN1KMT2AAKR1C1HSD11B1
SCHEMBL15756822 0.72 DPP4 (0.30)
SCHEMBL8585741 0.71 HPGD (0.33) MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899487-B Method for producing 5-hydroxypiperidine-2-carboxylic acid 株式会社API 2018-10-19 CN disclosed
CN-107573277-A The manufacture method of the formic acid of 5 hydroxy piperidine 2 株式会社API 2018-01-12 CN disclosed