SCHEMBL28743535

SCHEMBL28743535

O=C(O)N1CCCCC1(C(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
AKR1C1 Q04828 1/20 0.30
HSD11B1 P28845 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4800652 0.93 FFAR3 (0.31)
SCHEMBL572093 0.80
SCHEMBL9518563 0.78 CYP4F2 (0.32)
SCHEMBL1966290 0.77 CYP2C19 (0.30) CYP2C19MEN1KMT2A
SCHEMBL25365469 0.76 MEN1 (0.32) MEN1KMT2A
SCHEMBL31691566 0.76 MEN1 (0.32) MEN1KMT2A
SCHEMBL28236926 0.76 MEN1 (0.32) MEN1KMT2A
SCHEMBL17157143 0.76 FFAR3 (0.36)
SCHEMBL30101056 0.76
SCHEMBL17157141 0.76 FFAR3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1239434-A Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors VERTED PHARMACEUTICALS INC (US) 1999-12-22 CN disclosed