SCHEMBL940715

SCHEMBL940715

O=C(O)[C@@]1(O)CCCCN1O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3578695 1.00 CYP2C19 (0.31) CYP2C19MEN1KMT2A
SCHEMBL845602 0.93
SCHEMBL845600 0.93
SCHEMBL9762967 0.93
SCHEMBL4422891 0.83
SCHEMBL5072354 0.77 SLC6A1 (0.31)
SCHEMBL28200533 0.76 CYP2C19 (0.33) CYP2C19MEN1KMT2A
SCHEMBL23525345 0.76 FFAR3 (0.32) CYP2C19MEN1KMT2A
SCHEMBL1966290 0.76 CYP2C19 (0.30) CYP2C19MEN1KMT2A
SCHEMBL3009510 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210403424-A1 BIOACTIVE PHYTOCHEMICALS IN ZIZYPHUS AND GUARANA PHYTOQUEST LTD (GB) 2021-12-30 US disclosed
EP-3890729-A1 BIOACTIVE PHYTOCHEMICALS IN ZIZYPHUS AND GUARANA Phytoquest Limited (GB) 2021-10-13 EP disclosed
US-10842784-B2 Treatment of energy utilization disease VIDA PHARMA LIMITED (GB) 2020-11-24 US disclosed
WO-2020115475-A1 BIOACTIVE PHYTOCHEMICALS IN ZIZYPHUS AND GUARANA PHYTOQUEST LIMITED (GB) 2020-06-11 WO disclosed
EP-2257286-B1 TREATMENT OF ENERGY UTILIZATION DISEASE SUMMIT CORP PLC (GB) 2016-12-28 EP disclosed
US-20160151341-A1 TREATMENT OF ENERGY UTILIZATION DISEASE SUMMIT CORPORATION PLC (GB) 2016-06-02 US disclosed
US-20110015226-A1 Treatment of Energy Utilization Disease SUMMIT CORPORATION PLC (GB) 2011-01-20 US disclosed
EP-2257286-A1 TREATMENT OF ENERGY UTILIZATION DISEASE Summit Corporation Plc (GB) 2010-12-08 EP disclosed
WO-2009103953-A1 TREATMENT OF ENERGY UTILIZATION DISEASE SUMMIT CORPORATION PLC (GB) 2009-08-27 WO disclosed
EP-0439444-A2 Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors MONSANTO COMPANY (US) 1991-07-31 EP disclosed
US-5013842-A Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors MONSANTO COMPANY (US) 1991-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10842784-B2 Treatment of energy utilization disease IRS1, SLC2A1, INSR CYP2C19 2634/4885MEN1 1224/4885KMT2A 3165/4885
US-20110015226-A1 Treatment of Energy Utilization Disease IRS1, SLC2A1, INSR CYP2C19 2634/4885MEN1 1224/4885KMT2A 3165/4885
US-20210403424-A1 BIOACTIVE PHYTOCHEMICALS IN ZIZYPHUS AND GUARANA PRAP1, PEPD, PPIA CYP2C19 281/4885MEN1 4378/4885KMT2A 209/4885
US-20160151341-A1 TREATMENT OF ENERGY UTILIZATION DISEASE IRS1, SLC2A1, INSR CYP2C19 2634/4885MEN1 1224/4885KMT2A 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.