Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843972 | 0.84 | TDP1 (0.56) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL864716 | 0.83 | MAPT (0.61) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL10809629 | 0.79 | L3MBTL1 (0.59) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL291698 | 0.79 | L3MBTL1 (0.59) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL291697 | 0.79 | L3MBTL1 (0.59) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL28612997 | 0.79 | MAPT (0.56) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL9305304 | 0.79 | HPGD (0.62) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL8158863 | 0.79 | GSK3B (0.58) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL2388014 | 0.79 | TDP1 (0.56) | MAPTTDP1HPGDKMT2AMAPK1 | |
| SCHEMBL5852707 | 0.79 | MAPT (0.56) | MAPTTDP1HPGDKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573277-A | The manufacture method of the formic acid of 5 hydroxy piperidine 2 | 株式会社API | 2018-01-12 | — | — | CN | disclosed |