Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294710 | 0.85 | PROKR1 (0.63) | PROKR1HPGDTLR9TLR8TLR7 | |
| SCHEMBL15445063 | 0.85 | SIGMAR1 (0.64) | SIGMAR1HPGDMKNK1MKNK2CCNC | |
| SCHEMBL14872336 | 0.85 | PROKR1 (0.63) | PROKR1HPGD | |
| SCHEMBL25335789 | 0.84 | PROKR1 (0.56) | PROKR1HPGDL3MBTL1HRH4 | |
| SCHEMBL25335781 | 0.84 | PROKR1 (0.56) | PROKR1HPGDL3MBTL1HRH4 | |
| SCHEMBL28266262 | 0.83 | PROKR1 (0.53) | PROKR1HPGDKDM4E | |
| SCHEMBL7492026 | 0.81 | SIGMAR1 (0.54) | SIGMAR1PROKR1HPGDMKNK1MKNK2 | |
| SCHEMBL17689077 | 0.81 | HPGD (0.60) | PROKR1HPGDKDM4EL3MBTL1 | |
| SCHEMBL22601444 | 0.81 | LMNA (0.66) | SIGMAR1HPGDMKNK1MKNK2CCNC | |
| SCHEMBL21212583 | 0.80 | PROKR1 (0.57) | PROKR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107721943-A | Jie Gou oxazolidinone compounds of hydrazone containing biaryl and preparation method thereof | 沈阳药科大学 | 2018-02-23 | — | — | CN | disclosed |