Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199991 | 0.79 | BRD4 (0.35) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL28200012 | 0.78 | BRD4 (0.32) | — | |
| SCHEMBL15334046 | 0.74 | MAPK14 (0.48) | MAPK14CSNK1DGCGR | |
| SCHEMBL28229642 | 0.73 | MET (0.36) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL15334179 | 0.69 | CHRM1 (0.45) | — | |
| SCHEMBL14066949 | 0.68 | DYRK1A (0.54) | NFATC1GSK3BDYRK1AMAPK14MAPK13 | |
| SCHEMBL15333143 | 0.67 | CHRM1 (0.46) | — | |
| SCHEMBL27590581 | 0.66 | CYP11B1 (0.42) | DYRK1ACYP11B1CYP11B2CYP19A1MAPT | |
| SCHEMBL1644870 | 0.64 | MAPK14 (0.65) | NFATC1GSK3BDYRK1AMAPK14MAPK13 | |
| SCHEMBL28199937 | 0.64 | NR4A2 (0.33) | GSK3BMAPTKDRGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104185627-B | Pyridone Derivatives | 第三共株式会社 | 2018-01-12 | — | — | CN | disclosed |