SCHEMBL28200699

SCHEMBL28200699

NNC(=O)C(=O)Oc1cccc(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
PARP1 P09874 1/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
IDO1 P14902 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ATM Q13315 1/20 0.38
KCNN4 O15554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28051255 0.80 OGG1 (0.55) MEN1KMT2APARP1NPSR1IDO1
SCHEMBL9576776 0.78 TDP1 (0.42) MEN1KMT2ARAB9AHPGDALDH1A1
SCHEMBL9508323 0.77 ESR1 (0.49) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL443014 0.77 KMT2A (0.73) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL5487011 0.76 ESR1 (0.54) ESR1ESR2MEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL28147531 0.75 KMT2A (0.70) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL15763906 0.75 MEN1 (0.52) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL28200099 0.75 F2 (0.53) MEN1KMT2ACES2CES1ALDH1A1
SCHEMBL15836533 0.75 ELANE (0.49) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL18697278 0.74 ESR1 (0.53) ESR1ESR2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed