Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL28200701 | 0.83 | KCNN4 (0.48) | CES2CES1ALDH1A1KCNN4NPC1 | |
| Urea SCHEMBL27494998 | 0.82 | CES2 (0.55) | CES2CES1ALDH1A1ALOX15KCNN4 | |
| Hydrazine SCHEMBL27364486 | 0.82 | ACHE (0.50) | CES2CES1ALDH1A1ALOX15NPC1 | |
| Acetic Acid SCHEMBL27477632 | 0.80 | CES2 (0.52) | CES2CES1PTPN1ERCC5FEN1 | |
| Hydrazine SCHEMBL28200219 | 0.78 | ACHE (0.47) | CES2CES1ALDH1A1ALOX15NPC1 | |
| Hydrazine SCHEMBL28013386 | 0.78 | ACHE (0.47) | CES2CES1ALDH1A1ALOX15 | |
| Oxalic Acid SCHEMBL28378762 | 0.78 | CES2 (0.54) | CES2CES1ALDH1A1KCNN4BCHE | |
| Sulfuric Acid SCHEMBL28200869 | 0.78 | CES2 (0.44) | CES2CES1ALDH1A1ALOX15NPC1 | |
| Acetamide SCHEMBL28249676 | 0.78 | CES2 (0.50) | CES2CES1ALDH1A1ALOX15KCNN4 | |
| Phosphoric Acid SCHEMBL28200114 | 0.78 | CES2 (0.44) | CES2CES1PTPN1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |