Hydrazine

Hydrazine

SCHEMBL28200770

COc1ccc([N+](=O)[O-])cc1.NN

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.66
ALDH1A1 P00352 5/20 0.58
LMNA P02545 3/20 0.58
POLB P06746 1/20 0.58
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
KCNJ1 P48048 1/20 0.57
KCNH2 Q12809 1/20 0.57
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
MAPK1 P28482 2/20 0.55
HSD17B10 Q99714 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20328414 0.96 APP (0.70) APPALDH1A1LMNAPOLBMEN1
SCHEMBL492221 0.96 APP (0.70) APPALDH1A1LMNAPOLBMEN1
SCHEMBL20328415 0.96 APP (0.70) APPALDH1A1LMNAPOLBMEN1
SCHEMBL28853641 0.93 APP (0.68) APPALDH1A1LMNAPOLBMEN1
Hydrochloric Acid SCHEMBL15269629 0.93 APP (0.68) APPALDH1A1LMNAPOLBMEN1
SCHEMBL31096483 0.93 APP (0.68) APPALDH1A1LMNAPOLBMEN1
Ethane SCHEMBL10589507 0.93 APP (0.68) APPALDH1A1LMNAPOLBMEN1
SCHEMBL27548370 0.93 APP (0.68) APPALDH1A1LMNAPOLBMEN1
Nitromethane SCHEMBL11691874 0.91 APP (0.66) APPALDH1A1LMNAPOLBMEN1
Nitrogen SCHEMBL9082924 0.91 APP (0.66) APPALDH1A1LMNAPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed