SCHEMBL28853641

SCHEMBL28853641

COc1ccc([N+](=O)[O-])cc1.[NaH]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.68
LMNA P02545 4/20 0.60
ALDH1A1 P00352 4/20 0.60
POLB P06746 1/20 0.60
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
KCNJ1 P48048 1/20 0.58
KCNH2 Q12809 1/20 0.58
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58
MAOA P21397 1/20 0.57
MAOB P27338 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
MAPK1 P28482 2/20 0.56
HSD17B10 Q99714 2/20 0.56
TP53 P04637 2/20 0.56
CYP3A4 P08684 1/20 0.56
THRB P10828 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20328415 0.98 APP (0.70) APPLMNAALDH1A1POLBMEN1
SCHEMBL492221 0.98 APP (0.70) APPLMNAALDH1A1POLBMEN1
SCHEMBL20328414 0.98 APP (0.70) APPLMNAALDH1A1POLBMEN1
Ethane SCHEMBL10589507 0.95 APP (0.68) APPLMNAALDH1A1POLBMEN1
SCHEMBL27548370 0.95 APP (0.68) APPLMNAALDH1A1POLBMEN1
SCHEMBL31096483 0.95 APP (0.68) APPLMNAALDH1A1POLBMEN1
Hydrochloric Acid SCHEMBL15269629 0.95 APP (0.68) APPLMNAALDH1A1POLBMEN1
Nitromethane SCHEMBL11691874 0.93 APP (0.66) APPLMNAALDH1A1POLBMEN1
Nitrogen SCHEMBL9082924 0.93 APP (0.66) APPLMNAALDH1A1POLBMEN1
Hydrazine SCHEMBL28200770 0.93 APP (0.66) APPLMNAALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428709-A Cation direct dye 巴斯夫欧洲公司 2017-12-01 CN disclosed