Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492221 | 1.00 | APP (0.70) | APPALDH1A1LMNAPOLBNPC1 | |
| SCHEMBL20328415 | 1.00 | APP (0.70) | APPALDH1A1LMNAPOLBNPC1 | |
| SCHEMBL28853641 | 0.98 | APP (0.68) | APPALDH1A1LMNAPOLBNPC1 | |
| SCHEMBL27548370 | 0.98 | APP (0.68) | APPALDH1A1LMNAPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL15269629 | 0.98 | APP (0.68) | APPALDH1A1LMNAPOLBNPC1 | |
| SCHEMBL31096483 | 0.98 | APP (0.68) | APPALDH1A1LMNAPOLBNPC1 | |
| Ethane SCHEMBL10589507 | 0.98 | APP (0.68) | APPALDH1A1LMNAPOLBNPC1 | |
| Nitromethane SCHEMBL11691874 | 0.96 | APP (0.66) | APPALDH1A1LMNAPOLBNPC1 | |
| Nitrogen SCHEMBL9082924 | 0.96 | APP (0.66) | APPALDH1A1LMNAPOLBNPC1 | |
| Hydrazine SCHEMBL28200770 | 0.96 | APP (0.66) | APPALDH1A1LMNAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179144-A1 | NITRATION OF AROMATIC COMPOUNDS | ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179144-A1 | NITRATION OF AROMATIC COMPOUNDS | NOS2, NOS1, NOS3 | APP 1278/4885ALDH1A1 315/4885LMNA 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.