Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200107 | 0.87 | L3MBTL1 (0.45) | KMT2AHTTLMNAMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL28856221 | 0.85 | L3MBTL1 (0.43) | KMT2AHTTLMNAMEN1RAB9A | |
| Sulfuric Acid SCHEMBL28200149 | 0.84 | KMT2A (0.42) | KMT2AHTTLMNAMEN1RAB9A | |
| Phosphoric Acid SCHEMBL28200695 | 0.84 | HTT (0.42) | KMT2AHTTLMNAMEN1RAB9A | |
| Oxalic Acid SCHEMBL20984924 | 0.78 | KMT2A (0.52) | KMT2AHTTLMNAMEN1RAB9A | |
| Oxalic Acid SCHEMBL28200792 | 0.77 | ALDH1A1 (0.44) | KMT2ALMNAMEN1RAB9ANPC1 | |
| SCHEMBL20984927 | 0.75 | GAA (0.59) | KMT2AHTTLMNAMEN1RAB9A | |
| SCHEMBL9461863 | 0.75 | HTT (0.53) | KMT2AHTTLMNAMEN1RAB9A | |
| SCHEMBL20605197 | 0.75 | L3MBTL1 (0.50) | KMT2AHTTLMNAMEN1RAB9A | |
| SCHEMBL2097429 | 0.72 | KMT2A (0.66) | KMT2AHTTLMNAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |