Methyl Isobutyl Ketone

Methyl Isobutyl Ketone

SCHEMBL28201028

CC(=O)CC(C)C.CC(C)=O.CCCCCCC(=O)CCCCCC

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
KMT2A Q03164 3/20 0.53
MAPT P10636 1/20 0.53
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
FAAH O00519 1/20 0.44
MAPK1 P28482 1/20 0.44
HAO1 Q9UJM8 1/20 0.44
PPARG P37231 6/20 0.43
PPARD Q03181 6/20 0.43
PPARA Q07869 6/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
GPR84 Q9NQS5 4/20 0.43
TLR2 O60603 2/20 0.43
FABP4 P15090 2/20 0.43
PTPN1 P18031 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Isobutyl Ketone SCHEMBL28180590 0.96 ALDH1A1 (0.58) ALDH1A1TDP1KMT2AMAPTCES2
2-Decanone SCHEMBL10511757 0.88 ALDH1A1 (0.58) ALDH1A1TDP1KMT2ACES2CES1
Methyl Isobutyl Ketone SCHEMBL4469718 0.88 ALDH1A1 (0.70) ALDH1A1TDP1KMT2ACES2CES1
Dodecane SCHEMBL28230254 0.88 ALDH1A1 (0.70) ALDH1A1TDP1KMT2ACES2CES1
Methyl Nonyl Ketone SCHEMBL9717380 0.86 KMT2A (0.50) ALDH1A1TDP1KMT2AMAPTCES2
Methyl Isobutyl Ketone SCHEMBL9045794 0.86 ALDH1A1 (0.61) ALDH1A1TDP1KMT2ACES2CES1
Methyl Isobutyl Ketone SCHEMBL5000849 0.85 ALDH1A1 (0.74) ALDH1A1TDP1KMT2ACES2CES1
Methyl Isobutyl Ketone SCHEMBL2340589 0.85 ALDH1A1 (0.74) ALDH1A1TDP1KMT2ACES2CES1
Methyl Isobutyl Ketone SCHEMBL28071916 0.85 ALDH1A1 (0.54) ALDH1A1TDP1KMT2ACES2CES1
Dodecanoate SCHEMBL27819984 0.85 GPR84 (0.65) ALDH1A1TDP1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107567477-A Pull tab for food and/or beverage can PPG工业俄亥俄公司 2018-01-09 CN disclosed