Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201050 | 0.82 | POLB (0.59) | POLBHPGDL3MBTL1LMNAALDH1A1 | |
| SCHEMBL28201023 | 0.80 | TDP1 (0.64) | POLBEPHX1HPGDEPHX2ALDH1A1 | |
| SCHEMBL8158999 | 0.78 | LMNA (0.73) | POLBEPHX1HPGDEPHX2LMNA | |
| SCHEMBL17875071 | 0.78 | EPHX1 (0.78) | POLBEPHX1HPGDL3MBTL1L3MBTL3 | |
| SCHEMBL8158991 | 0.77 | LMNA (0.67) | POLBEPHX1HPGDEPHX2LMNA | |
| SCHEMBL8595777 | 0.76 | POLB (0.87) | POLBLMNAALDH1A1MAPTTSHR | |
| SCHEMBL3641476 | 0.75 | GRM5 (0.67) | POLBEPHX1HPGDEPHX2LMNA | |
| SCHEMBL16944500 | 0.75 | EPHX1 (0.59) | POLBEPHX1HPGDL3MBTL1L3MBTL3 | |
| SCHEMBL16948781 | 0.75 | EPHX1 (0.59) | POLBEPHX1HPGDL3MBTL1L3MBTL3 | |
| SCHEMBL14368336 | 0.75 | EPHX1 (0.68) | POLBEPHX1HPGDL3MBTL1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652270-A | 2‑（4 morpholinyls）4,6 disubstituted pyrimidines/s-triazine compound and its salt and application | 西安交通大学 | 2018-02-02 | — | — | CN | disclosed |