Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201049 | 0.82 | POLB (0.58) | POLBMEN1KMT2ASLC6A7HPGD | |
| SCHEMBL17832734 | 0.79 | LTA4H (0.56) | POLBMEN1KMT2ASLC6A7USP2 | |
| SCHEMBL10721777 | 0.78 | MEN1 (0.87) | POLBMEN1KMT2ASLC6A7ALDH1A1 | |
| SCHEMBL7288482 | 0.77 | EPHX1 (0.69) | MEN1KMT2AHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL13034163 | 0.76 | L3MBTL3 (0.80) | POLBMEN1KMT2ASLC6A7L3MBTL1 | |
| SCHEMBL19562172 | 0.75 | MEN1 (0.67) | POLBMEN1KMT2ASLC6A7ALDH1A1 | |
| SCHEMBL8595777 | 0.74 | POLB (0.87) | POLBMEN1KMT2ASLC6A7ALDH1A1 | |
| SCHEMBL6825013 | 0.74 | ALDH1A1 (0.57) | POLBSLC6A7HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL911653 | 0.73 | L3MBTL1 (0.60) | POLBMEN1KMT2ASLC6A7HPGD | |
| SCHEMBL911595 | 0.73 | L3MBTL1 (0.60) | POLBMEN1KMT2ASLC6A7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652270-A | 2‑（4 morpholinyls）4,6 disubstituted pyrimidines/s-triazine compound and its salt and application | 西安交通大学 | 2018-02-02 | — | — | CN | disclosed |