Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879863 | 0.83 | LOXL2 (0.57) | LOXL2ENPP2CFDPNMTFOLH1 | |
| SCHEMBL28879968 | 0.83 | LOXL2 (0.57) | LOXL2ENPP2CFDPNMTFOLH1 | |
| SCHEMBL2643707 | 0.83 | LOXL2 (0.62) | LOXL2ENPP2CFDPNMTFOLH1 | |
| SCHEMBL27280115 | 0.83 | LOXL2 (0.57) | LOXL2ENPP2CFDPNMTFOLH1 | |
| SCHEMBL27594322 | 0.82 | LOXL2 (0.65) | LOXL2ENPP2CFDPNMTFOLH1 | |
| SCHEMBL28067316 | 0.81 | LOXL2 (0.60) | LOXL2ENPP2CFDFOLH1HTR2C | |
| Ethane SCHEMBL27753883 | 0.81 | LOXL2 (0.60) | LOXL2ENPP2CFDPNMTFOLH1 | |
| SCHEMBL12235278 | 0.81 | TDP1 (0.48) | TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11635523 | 0.81 | FOLH1 (0.43) | LOXL2FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL924897 | 0.81 | CYP4F2 (0.49) | LOXL2FOLH1CYP4F2CYP4A11HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995176-B | Hydantoins that modulate BACE mediated APP processing | 巴克老龄化研究所 | 2019-02-22 | — | — | CN | disclosed |
| CN-107793374-A | A kind of preparation method of 2 bromine 1 (3 methoxyphenyl) oxazoles | 湖南华腾制药有限公司 | 2018-03-13 | — | — | CN | disclosed |