Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794488 | 0.87 | GABBR2 (0.42) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL9677711 | 0.79 | HTR2A (0.43) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL6803229 | 0.79 | LMNA (0.48) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL3954689 | 0.79 | GABBR2 (0.41) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL19812663 | 0.79 | GABBR2 (0.55) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL11796860 | 0.78 | GABBR2 (0.36) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL9572611 | 0.76 | AOC3 (0.43) | GABBR2GABBR1CYP1A2CYP2D6PKM | |
| SCHEMBL833319 | 0.75 | HTR2A (0.46) | CYP2D6LMNAMAPK1TSHRKDM4E | |
| SCHEMBL8181819 | 0.74 | LMNA (0.38) | CYP2D6LMNAMAPK1TSHRKDM4E | |
| SCHEMBL3938453 | 0.72 | CYP2C19 (0.39) | GABBR2GABBR1CYP1A2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520277-B | Enkephalinase inhibitors | 施万生物制药研发IP有限责任公司 | 2018-01-19 | — | — | CN | disclosed |