Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL16987408 | 0.94 | TSHR (0.37) | TSHR | |
| Hydrochloric Acid SCHEMBL28345550 | 0.80 | TSHR (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL1914718 | 0.80 | SLC22A1 (0.38) | TSHR | |
| Hydrochloric Acid SCHEMBL27678093 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL93723 | 0.78 | — | — | |
| SCHEMBL27929931 | 0.77 | SLC22A1 (0.40) | TSHR | |
| Hydrochloric Acid SCHEMBL11571349 | 0.76 | TSHR (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL28048810 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL11584438 | 0.75 | TSHR (0.37) | TSHRKDM4EPMP22ATM | |
| Hydrochloric Acid SCHEMBL4729041 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104784685-B | The preparation method of the hydroxypropyl dimethyl ethyl ammonium chloride chitosan/carboxymethyl chitosan NDV nanoparticles of N 2 | 黑龙江大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-104784685-B | The preparation method of the hydroxypropyl dimethyl ethyl ammonium chloride chitosan/carboxymethyl chitosan NDV nanoparticles of N 2 | 黑龙江大学 | 2018-03-13 | — | — | CN | disclosed |