Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929931 | 0.97 | SLC22A1 (0.40) | SLC22A1TSHR | |
| SCHEMBL28558284 | 0.82 | SLC22A1 (0.39) | SLC22A1TSHRPSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL27991373 | 0.81 | DNM1 (0.50) | SLC22A1PLA2G1BRAD52ATG4B | |
| Hydrochloric Acid SCHEMBL28388151 | 0.81 | DNM1 (0.50) | SLC22A1PLA2G1BRAD52ATG4B | |
| Hydrochloric Acid SCHEMBL28385909 | 0.81 | DNM1 (0.50) | SLC22A1PLA2G1BRAD52ATG4B | |
| Hydrochloric Acid SCHEMBL19436590 | 0.81 | DNM1 (0.50) | SLC22A1PLA2G1BRAD52ATG4B | |
| Hydrochloric Acid SCHEMBL28201228 | 0.80 | TSHR (0.37) | TSHR | |
| Hydrochloric Acid SCHEMBL11571349 | 0.80 | TSHR (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL1958103 | 0.78 | SOAT1 (0.46) | — | |
| SCHEMBL97959 | 0.78 | DNM1 (0.48) | SLC22A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106592335-A | Novel cation rosin sizing agent used for food packaging paper | 南昌市龙然实业有限公司 | 2017-04-26 | — | — | CN | claimed |
| US-20240099955-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | HTL BIOTECHNOLOGY INNOVATION INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4288084-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | Modern Meadow, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116360028-A | Polarizing plate with surface protective film | 日东电工株式会社 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022170114-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | MODERN MEADOW, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-110699689-B | Diamond film and preparation method and application thereof | 深圳先进技术研究院 | 2022-05-24 | — | — | CN | disclosed |
| CN-110699689-A | Diamond film and preparation method and application thereof | 深圳先进技术研究院 | 2020-01-17 | — | — | CN | disclosed |
| CN-108137820-A | Cosmetic composition, cosmetic and external preparation for skin | 道康宁东丽株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-104981500-B | Low platinum content hydrosilylation bridging property silicone rubber powder | 道康宁东丽株式会社 | 2018-05-18 | — | — | CN | disclosed |
| CN-104661645-B | Copolymer with carbon siloxanes dendritic structure and include its composition and cosmetics | 道康宁东丽株式会社 | 2018-05-15 | — | — | CN | disclosed |
| CN-103079538-A | Cosmetic for hair comprising co-modified organopolysiloxane | DOW CORNING TORAY CO LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-103079539-A | Cosmetic for hair containing sugar alcohol-modified silicone | DOW CORNING TORAY CO LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-101918475-B | Method of producing amino acid-modified organopolysiloxane emulsions | DOW CORNING TORAY CO LTD | 2013-03-06 | — | — | CN | disclosed |
| CN-102947369-A | Organopolysiloxane and use thereof as surfactant, powder treatment agent, thickening agent of oil -based raw material or gelling agent. gel and emulsion compositions, as well as, preparations for external use and cosmetics comprising the same | DOW CORNING TORAY CO LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-102906161-A | Novel organopolysiloxane, surfactant, emulsion composition, powder treatment agent, thickening agent of oil-based raw material, gelling agent, gel composition, and cosmetic raw material comprising novel organopolysiloxane, as well as, preparation for external use and cosmetic comprising the same | DOW CORNING TORAY CO LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-101227889-B | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY CO LTD | 2012-11-07 | — | — | CN | disclosed |
| EP-2515841-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078407-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-30 | — | — | WO | disclosed |
| CN-101918475-A | Produce the method for amino-acid modified organopolysiloxane emulsion | DOW CORNING TORAY CO LTD | 2010-12-15 | — | — | CN | disclosed |
| CN-101227889-A | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |