Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Chloride SCHEMBL5174926 | 0.86 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL28202581 | 0.83 | STAT3 (0.41) | TSHRALDH1A1STAT3STAT1 | |
| SCHEMBL28141199 | 0.83 | STAT3 (0.31) | STAT3STAT1GPR84KCNH2 | |
| SCHEMBL27845740 | 0.83 | STAT3 (0.31) | STAT3STAT1GPR84KCNH2 | |
| Methylene Chloride SCHEMBL27864612 | 0.82 | STAT3 (0.38) | STAT3STAT1 | |
| Butyl Alcohol SCHEMBL27909152 | 0.81 | ALDH1A1 (0.38) | TSHRALDH1A1STAT3STAT1GPR84 | |
| Methylene Chloride SCHEMBL28114984 | 0.80 | STAT3 (0.37) | STAT3STAT1 | |
| SCHEMBL28761349 | 0.78 | STAT3 (0.36) | STAT3STAT1 | |
| Alcohol SCHEMBL1345780 | 0.78 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL29430977 | 0.78 | STAT3 (0.42) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641203-B | A3B-type monothioporphyrin compound and its preparation method and use | 山东师范大学 | 2020-09-29 | — | — | CN | disclosed |
| CN-107652445-B | A3B-type monothioporphyrin modified metal organic framework nano material and preparation method and application thereof | 山东师范大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-107652445-A | A kind of A3Porphyrin modified metal organic frame nano material of Type B list sulfydryl and its production and use | 山东师范大学 | 2018-02-02 | — | — | CN | disclosed |
| CN-107641203-A | A kind of A3Type B list sulfydryl porphyrin compound and its production and use | 山东师范大学 | 2018-01-30 | — | — | CN | disclosed |