Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Dimethylaminophenol SCHEMBL28321967 | 0.93 | APP (0.50) | APPALDH1A1MEN1NPC1KMT2A | |
| Catechol SCHEMBL28201430 | 0.85 | MCL1 (0.36) | APPALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL2593615 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1NPC1KMT2ARAB9A | |
| Trimethylammonium SCHEMBL27539581 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MEN1NPC1KMT2ARAB9A | |
| Catechol SCHEMBL28107703 | 0.73 | CA12 (0.55) | ALDH1A1MEN1NPC1KMT2ARAB9A | |
| 4-Dimethylaminophenol SCHEMBL224308 | 0.73 | APP (0.73) | APPALDH1A1MEN1NPC1KMT2A | |
| 4-Dimethylaminophenol SCHEMBL9792507 | 0.73 | APP (0.73) | APPALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL543678 | 0.73 | ALDH1A1 (0.69) | APPALDH1A1MEN1KMT2AMAPT | |
| Phenol SCHEMBL1702877 | 0.71 | CA12 (0.58) | ALDH1A1MEN1NPC1KMT2ARAB9A | |
| Benzenethiol SCHEMBL9714715 | 0.71 | CA2 (0.45) | ALDH1A1MEN1NPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698766-A | Curable compositions, method, purposes and the device of side chain polysiloxane and correlation | 道康宁公司 | 2018-02-16 | — | — | CN | disclosed |