Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201976 | 0.88 | LOXL2 (0.46) | HDAC6LIPG | |
| SCHEMBL203384 | 0.83 | PIK3CA (0.44) | HDAC6LIPGKDM4EPIK3CAPI4KA | |
| SCHEMBL2956510 | 0.81 | LOXL2 (0.62) | HDAC6NPC1HPGDRAB9AMEN1 | |
| SCHEMBL5074923 | 0.81 | AKR1B1 (0.46) | HDAC6KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL3190308 | 0.81 | KDM4E (0.51) | HDAC6KDM4ENPC1HPGDNFKB1 | |
| SCHEMBL28984547 | 0.81 | MAPT (0.47) | HDAC6KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL28984552 | 0.81 | HDAC6 (0.55) | HDAC6KDM4ENPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL3898824 | 0.80 | KDM4E (0.50) | HDAC6KDM4ENPC1HPGDNFKB1 | |
| SCHEMBL1127709 | 0.80 | UBE2T (0.61) | KDM4ENPC1HPGDRAB9AMEN1 | |
| SCHEMBL12596792 | 0.78 | PIK3CA (0.58) | LIPGKDM4EPIK3CAPI4KAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |