Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201449 | 0.88 | HDAC6 (0.49) | HDAC6LIPG | |
| SCHEMBL2956510 | 0.82 | LOXL2 (0.62) | LOXL2HDAC6PTGDR2 | |
| SCHEMBL203384 | 0.75 | PIK3CA (0.44) | LOXL2HDAC6LIPG | |
| SCHEMBL6975411 | 0.74 | LOXL2 (0.52) | LOXL2HDAC6 | |
| SCHEMBL10340748 | 0.74 | AKR1B1 (0.53) | LOXL2HDAC6PTGDR2 | |
| SCHEMBL584581 | 0.72 | LOXL2 (0.74) | LOXL2HDAC6 | |
| SCHEMBL27520626 | 0.72 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL12596792 | 0.71 | PIK3CA (0.58) | LIPG | |
| SCHEMBL2705988 | 0.71 | LOXL2 (0.54) | LOXL2HDAC6 | |
| SCHEMBL3190308 | 0.71 | KDM4E (0.51) | LOXL2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |