Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916161 | 0.78 | PYCR1 (0.43) | SLC5A2GAAMAPTLMNATSHR | |
| SCHEMBL157269 | 0.78 | KDM4E (0.44) | ALDH1A1GAAMAPTL3MBTL1LMNA | |
| SCHEMBL3296809 | 0.77 | IDO1 (0.61) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL11522551 | 0.75 | NPC1 (0.39) | SLC5A2IDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL12782037 | 0.75 | TAAR1 (0.47) | SLC5A2IDO1TAAR1ALDH1A1MAPT | |
| SCHEMBL28201919 | 0.75 | TAAR1 (0.47) | SLC5A2IDO1TAAR1ALDH1A1CYP1A2 | |
| SCHEMBL17939 | 0.75 | IDO1 (0.59) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL265951 | 0.73 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL1682187 | 0.73 | LTA4H (0.52) | SLC5A2IDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL7339450 | 0.72 | SLC5A2 (0.55) | SLC5A2ADORA2AADORA1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |