Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.39 |
| ▸ | TUBB | P07437 | 4/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775820 | 0.80 | CYP2A6 (0.44) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL155195 | 0.77 | CYP2A6 (0.42) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL28954990 | 0.76 | CYP2A6 (0.47) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL1773869 | 0.72 | CYP2A6 (0.47) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL16018691 | 0.72 | CYP2A6 (0.42) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL6958014 | 0.71 | TUBB4A (0.53) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL1539306 | 0.71 | SLC5A2 (0.55) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL12425721 | 0.71 | SLC5A2 (0.50) | CYP2A6AGXTADRB2ASIC3LOXL2 | |
| SCHEMBL29227832 | 0.70 | ALDH1A1 (0.48) | CYP2A6TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4961407 | 0.70 | CYP2A6 (0.69) | CYP2A6AGXTADRB2ASIC3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |