SCHEMBL28201494

SCHEMBL28201494

Brc1ccc(I)cc1.Brc1cccc(I)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 2/20 0.41
APP P05067 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAOB P27338 1/20 0.38
CYP2A6 P11509 2/20 0.38
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
CYP1A2 P05177 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
C1S P09871 1/20 0.34
PARP1 P09874 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
IDO1 P14902 3/20 0.33
AGXT P21549 2/20 0.33
CNR1 P21554 1/20 0.33
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30268524 0.90
SCHEMBL79244 0.90
SCHEMBL9574884 0.87
Ammonia Solution, Strong SCHEMBL6118165 0.87
Methyl Alcohol SCHEMBL27406621 0.83 ALDH1A1 (0.48) ALDH1A1MAPK1APPMEN1CYP1A2
Cyanide SCHEMBL27957952 0.83 ALDH1A1 (0.42) ALDH1A1MAPK1TDP1MEN1NPC1
Iodobenzene SCHEMBL22799141 0.79 ALDH1A1 (0.56) ALDH1A1MAPK1APPTDP1MAOB
SCHEMBL22384032 0.79 ALDH1A1 (0.62) ALDH1A1MAPK1APPTDP1MAOB
SCHEMBL8068361 0.79 CYP2A6 (0.61) ALDH1A1MAPK1APPTDP1CYP2A6
SCHEMBL455656 0.79 CYP2A6 (0.61) ALDH1A1MAPK1APPTDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640848-B Anthracene derivative and organic electroluminescent element using same 出光兴产株式会社 2018-01-26 CN disclosed