SCHEMBL455656

SCHEMBL455656

Brc1ccc(I)cc1.Brc1ccc(I)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.61
APP P05067 1/20 0.52
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 2/20 0.44
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 1/20 0.41
CNR1 P21554 1/20 0.41
CA2 P00918 4/20 0.38
CA1 P00915 3/20 0.38
TSHR P16473 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HDAC8 Q9BY41 1/20 0.37
TPMT P51580 1/20 0.36
GSK3B P49841 2/20 0.36
HTR2A P28223 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8068361 1.00 CYP2A6 (0.61) CYP2A6APPALDH1A1ALOX15MAPK1
SCHEMBL24146 1.00
Fluoride SCHEMBL5504537 0.93 CYP2A6 (0.53) CYP2A6APPALDH1A1ALOX15MAPK1
SCHEMBL74194 0.90 ALDH1A1 (0.55) CYP2A6APPALDH1A1ALOX15MAPK1
SCHEMBL10356669 0.90 ALDH1A1 (0.55) CYP2A6APPALDH1A1ALOX15MAPK1
Iodobenzene SCHEMBL22799141 0.87 ALDH1A1 (0.56) CYP2A6APPALDH1A1ALOX15MAPK1
SCHEMBL17818509 0.85 CYP2A6 (0.44) CYP2A6APPALDH1A1ALOX15MAPK1
SCHEMBL23800916 0.83 CYP2A6 (0.42) CYP2A6APPALDH1A1ALOX15MAPK1
SCHEMBL2601888 0.83 APP (0.52) CYP2A6APPALDH1A1
SCHEMBL8142840 0.83 MAOA (0.52) CYP2A6APPMAPK1CNR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304514-B2 Conjugated polymer, method for preparing the same, and optoelectronic device employing the same NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2012-11-06 US disclosed
US-20120017994-A1 CONJUGATED POLYMER, METHOD FOR PREPARING THE SAME, AND OPTOELECTRONIC DEVICE EMPLOYING THE SAME NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2012-01-26 US disclosed