Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.47 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221518 | 0.90 | LMNA (0.62) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| SCHEMBL30449216 | 0.90 | LMNA (0.62) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| SCHEMBL27815764 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL2533965 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| SCHEMBL27794599 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| SCHEMBL9461001 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27794593 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| SCHEMBL29208535 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| SCHEMBL27815762 | 0.88 | LMNA (0.60) | LMNAGAATAS2R14ALDH1A1MEN1 | |
| Ethylene SCHEMBL714453 | 0.86 | LMNA (0.58) | LMNAGAATAS2R14ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107565033-A | Nickel oxide film and preparation method thereof, functional material, the preparation method of membrane structure and electroluminescent device | 浙江大学 | 2018-01-09 | — | — | CN | disclosed |