SCHEMBL28201713

SCHEMBL28201713

CCCCc1ccc(C(=NC(N)=O)c2ccccc2)c(CCCC)c1[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.34
AGTR2 P50052 1/20 0.34
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
KMT2A Q03164 2/20 0.33
CNR2 P34972 4/20 0.33
MAPT P10636 1/20 0.33
ELANE P08246 1/20 0.32
CTRC Q99895 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28202467 0.91 MAPT (0.33) CES2CES1KMT2ACNR2MAPT
SCHEMBL28201889 0.85 ALDH1A1 (0.34) CES2CES1KMT2AMAPTSMN1; SMN2
SCHEMBL28856660 0.79 KMT2A (0.35) KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL28476637 0.76 TYR (0.41) KMT2AMAPTLMNASMN1; SMN2TRPV1
SCHEMBL28856441 0.75 ALDH1A1 (0.40) CES2CES1KMT2AMAPTLMNA
SCHEMBL27806438 0.71 CES2 (0.40) CES2CES1KMT2ACNR2MAPT
SCHEMBL4657626 0.70 TLR8 (0.47) TRPV1ALDH1A1TDP1
SCHEMBL11792221 0.70 SKP2 (0.39) KMT2AMAPTCTRCLMNASMN1; SMN2
SCHEMBL7340241 0.69 MEN1 (0.40) KMT2AMAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL28201737 0.69 BCL2 (0.35) CES2CES1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107778210-A The synthetic method of 3 selenoindoles class compounds 苏州大学 2018-03-09 CN disclosed