Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108421 | 0.82 | CA2 (1.00) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL11407481 | 0.81 | CA2 (0.96) | CA2CA1CA9F2PRSS1 | |
| Indole SCHEMBL28853217 | 0.73 | CA2 (0.53) | CA2CA1CA9TRPA1ITGB2 | |
| SCHEMBL18669851 | 0.72 | CA2 (0.63) | CA2CA1CA9F2PRSS1 | |
| Sulfamide SCHEMBL3360909 | 0.71 | CA2 (0.61) | CA2CA1CA9F2PRSS1 | |
| SCHEMBL337953 | 0.71 | AHR (0.52) | CA2CA1CA9CA4CA6 | |
| SCHEMBL12861124 | 0.70 | CA2 (0.75) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL532348 | 0.70 | CA2 (0.75) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8149846 | 0.70 | CA2 (0.64) | CA2CA1CA9F2PRSS1 | |
| Indole SCHEMBL6191820 | 0.69 | CA1 (0.49) | CA2CA1CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107760299-A | 6 dansyl amide indoles fluorescence probes and preparation method and application | 山东朱氏堂医疗器械有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107760299-A | 6 dansyl amide indoles fluorescence probes and preparation method and application | 山东朱氏堂医疗器械有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107746382-A | 4 dansyl amide indoles fluorescence probes and preparation method and application | 山东朱氏堂医疗器械有限公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-107746382-A | 4 dansyl amide indoles fluorescence probes and preparation method and application | 山东朱氏堂医疗器械有限公司 | 2018-03-02 | — | — | CN | disclosed |