SCHEMBL11407481

SCHEMBL11407481

CN(C)c1cccc2c(S(N)(=O)=O)cccc12.[Na]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.96
F2 P00734 3/20 0.60
PRSS1 P07477 3/20 0.60
PRSS2 P07478 3/20 0.60
PRSS3 P35030 3/20 0.60
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
HTT P42858 1/20 0.59
HIF1A Q16665 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 1/20 0.56
ATM Q13315 1/20 0.56
CDK2 P24941 1/20 0.55
EDNRA P25101 8/20 0.54
CA1 P00915 1/20 0.52
CA9 Q16790 1/20 0.52
KDM4E B2RXH2 1/20 0.50
NSD2 O96028 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108421 0.98 CA2 (1.00) CA2F2PRSS1PRSS2PRSS3
SCHEMBL12861124 0.84 CA2 (0.75) CA2F2PRSS1PRSS2PRSS3
SCHEMBL532348 0.84 CA2 (0.75) CA2F2PRSS1PRSS2PRSS3
SCHEMBL28726368 0.83 CA2 (0.71) CA2F2PRSS1PRSS2PRSS3
SCHEMBL30958757 0.82 CA2 (0.67) CA2F2PRSS1PRSS2PRSS3
SCHEMBL9019311 0.81 CA2 (0.71) CA2F2PRSS1PRSS2PRSS3
SCHEMBL1131010 0.81 CA2 (0.71) CA2F2PRSS1PRSS2PRSS3
SCHEMBL5720805 0.81 CA2 (0.70) CA2F2PRSS1PRSS2PRSS3
Indole SCHEMBL28201813 0.81 CA2 (0.68) CA2F2PRSS1PRSS2PRSS3
SCHEMBL9138970 0.80 CDK2 (0.78) CA2TDP1L3MBTL1CDK2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55110955-A None JP disclosed
JP-S55110955-A NOVEL FLUORESCENT ESTIMATION OF PHENYLTHIOHYDANITON AMINO ACID YUKI GOSEI YAKUHIN KOGYO KK 1980-08-27 JP disclosed