SCHEMBL28201831

SCHEMBL28201831

CC(C)(O)c1cc(N)ccc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 4/20 0.40
POLB P06746 2/20 0.40
GAA P10253 2/20 0.40
GLA P06280 1/20 0.40
CASP1 P29466 4/20 0.39
RECQL P46063 4/20 0.38
THRB P10828 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
PKM P14618 2/20 0.38
KMT2A Q03164 2/20 0.38
USP2 O75604 1/20 0.38
APEX1 P27695 1/20 0.38
BLM P54132 1/20 0.38
MCL1 Q07820 1/20 0.38
PDE10A Q9Y233 1/20 0.37
CYP3A4 P08684 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17312034 0.83 SMN1; SMN2 (0.39) PGRSMN1; SMN2TSHRPOLBGAA
SCHEMBL9503147 0.81 TSHR (0.43) PGRSMN1; SMN2TSHRPOLBGAA
SCHEMBL3291266 0.80 SMN1; SMN2 (0.63) PGRSMN1; SMN2TSHRPOLBTHRB
SCHEMBL6678297 0.79 SMN1; SMN2 (0.37) PGRSMN1; SMN2TSHRPOLBGAA
SCHEMBL10002095 0.79 SMN1; SMN2 (0.49) PGRSMN1; SMN2TSHRPOLBGAA
SCHEMBL24526314 0.78 TSHR (0.38) PGRTSHRPOLBGAAGLA
SCHEMBL78315 0.78 PGR (0.49) PGRSMN1; SMN2TSHRPOLBGLA
SCHEMBL30057257 0.78 TSHR (0.38) PGRTSHRPOLBGAAGLA
SCHEMBL1248161 0.78 PGR (0.49) PGRSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL18874465 0.78 PGR (0.67) PGRSMN1; SMN2TSHRGAARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110126396-A A kind of lamination composite damping sheets and preparation method thereof 浙江工业大学 2019-08-16 CN claimed
CN-106188698-B A kind of heat-resisting oil resistant rubber sealing ring and preparation method thereof 珠海海源密封胶有限公司 2018-03-06 CN claimed
CN-106188698-A A kind of heat-resisting oil resistant rubber sealing ring and preparation method thereof 樊之雄 2016-12-07 CN claimed
CN-110054857-A A kind of ultralow smoke density rubber damping piece and preparation method thereof 浙江工业大学 2019-07-26 CN disclosed
CN-109306090-A A kind of oil resistant sterilization sealing ring and preparation method thereof 江苏伊顿航天材料股份有限公司 2019-02-05 CN disclosed
CN-106188698-B A kind of heat-resisting oil resistant rubber sealing ring and preparation method thereof 珠海海源密封胶有限公司 2018-03-06 CN disclosed
CN-106188698-B A kind of heat-resisting oil resistant rubber sealing ring and preparation method thereof 珠海海源密封胶有限公司 2018-03-06 CN disclosed
CN-106188698-A A kind of heat-resisting oil resistant rubber sealing ring and preparation method thereof 樊之雄 2016-12-07 CN disclosed
CN-106188698-A A kind of heat-resisting oil resistant rubber sealing ring and preparation method thereof 樊之雄 2016-12-07 CN disclosed